Recombinant human Recombinant human Cyclophilin A protein

Relevance: Cyclophilin A, also called peptidylisomeras A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis­ and trans­ proline residues critical for proper folding of proteins. Cyclophilin is also incorporated into many viruses, including HIV­1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
Product Info: GST tagged
Source: E.coli derived
Purity: 90%
Image:
Tested applications: ELISA, Western blot
Storage Buffer: PBS buffer, 20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence: mvnptvffdiavdgeplgrv sfelfadkvpktaenfrals tgekgfgykgscfhriipgf mcqggdftrh ngtggksiyg ekfedenfil khtgpgilsm anagpntngsqffi ctakte wldgkhvvfg kvkegmnive amerfgsrng ktskkitiad cgqle
Referrences: [1] "Complementary DNA for human T-cell cyclophilin." Haendler B., Hofer-Warbinek R., Hofer E. EMBO J. 6:947-950(1987) [2] "Characterization of the human cyclophilin gene and of related processed pseudogenes." Haendler B., Hofer E. Eur. J. Biochem. 190:477-482(1990)
Alias: Cyclophilin A,Cyclosporin A-binding protein,Rotamase A.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	10 мкг
	Кат. номер:	CSB-RP078144h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Recombinant human Cyclophilin A protein. Примечание: дополнительная информация (на английском языке).