Recombinant human Tropomyosin beta chain protein

Relevance: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization By similarity.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: 20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0,200 mM Imidazole
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism." MacLeod A.R., Houlker C., Reinach F.C., Smillie L.B., Talbot K., Modi G., Walsh F.S. Proc. Natl. Acad. Sci. U.S.A. 82:7835-7839(1985) [PubMed: 3865200] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2). Tissue: Fibroblast. [2] "Complete nucleotide sequence of the adult skeletal isoform of human skeletal muscle beta-tropomyosin." Widada J.S., Ferraz C., Capony J.-P., Liautard J.-P. Nucleic Acids Res. 16:3109-3109(1988) [PubMed: 3368322] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). [3] "A cDNA encoding a muscle-type tropomyosin cloned from a human epithelial cell line: identity with human fibroblast tropomyosin TM1." Prasad G.L., Meissner S., Sheer D.G., Cooper H.L. Biochem. Biophys. Res. Commun. 177:1068-1075(1991) [PubMed: 2059197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Tissue: Colon epithelium.
Alias: Beta-tropomyosin Tropomyosin-2.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	10 мкг
	Кат. номер:	CSB-RP133874h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Tropomyosin beta chain protein. Примечание: дополнительная информация (на английском языке).