Recombinant human Troponin I, cardiac muscle protein

Relevance: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Defects in TNNI3 are the cause of cardiomyopathy familial hypertrophic type 7 (CMH7) [MIM:613690]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
Product Info:
Source:
Purity: 95%
Image:
Tested applications: ELISA, Western blot, PETIA
Storage Buffer: PBS buffer
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Troponin I isoform expression in human heart." Hunkeler N.M., Kullman J., Murphy A.M. Circ. Res. 69:1409-1414(1991) [2] "Isolation and characterization of the human cardiac troponin I gene (TNNI3)." Bhavsar P.K., Brand N.J., Yacoub M.H., Barton P.J.R. Genomics 35:11-23(1996)
Alias: Cardiac troponin I.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	1 мг
	Кат. номер:	CSB-RP079374h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Troponin I, cardiac muscle protein. Примечание: дополнительная информация (на английском языке).