Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein

Relevance: Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
Product Info: His tagged
Source: E.coli derived
Purity: 95%
Image:

Tested applications: SDS-PAGE, ELISA
Storage Buffer: PBS buffer
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence: QPYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFRTTW
Referrences: [1] Lange C.A., Blumer K.J., Sather S.L., Johnson G.L. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [2] "JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway." Ito M., Yoshioka K., Akechi M., Yamashita S., Takamatsu N., Sugiyama K., Hibi M., Nakabeppu Y., Shiba T., Yamamoto K. Mol. Cell. Biol. 19:7539-7548(1999) [PubMed: 10523642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-659. Tissue: Spleen. [3] "A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf." Lange-Carter C.A., Pleiman C.M., Gardner A.M., Blumer K.J., Johnson G.L. Science 260:315-319(1993) [PubMed: 8385802] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 660-1493. Strain: BALB/c. Tissue: Brain.
Alias: MAPK/ERK kinase kinase 1.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	200 мкг
	Кат. номер:	CSB-RP152894m
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein. Примечание: дополнительная информация (на английском языке).