Recombinant Streptolysin O protein

Relevance: Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: ELISA, Western blot
Storage Buffer: 20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0; 200 mM Imidazole
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1]"Cloning and sequencing the streptolysin O genes of group C and group G streptococci." Okumura K., Hara A., Tanaka T., Nichiguchi I., Minamide W., Igarashi H., Yutsudo T. DNA Seq. 4:325-328(1994)
Alias: Thiol-activated cytolysin.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	200 мкг
	Кат. номер:	CSB-RP078074Ba
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant Streptolysin O protein. Примечание: дополнительная информация (на английском языке).