P-Selectin/CD62P/SELP Antibody (P8G6) PE

P-Selectin (P8G6) PE

Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

 

• P-Selectin/CD62P/SELP Antibody (P8G6) is a mouse monoclonal IgG₁ κ, cited in 7 publications, provided at 200 µg/ml
• raised against IL-1β activated HUV-EC cells expressing full length P-Selectin
• recommended for detection of P-Selectin of human origin by IP, IF, IHC(P), FCM and ELISA
• available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
• also provided azide-free for inhibiting P-Selectin dependent interactions and inhibiting platelet binding to monocytes, sc-18834 L, 200 µg/0.1 ml
• See P-Selectin/CD62P/SELP (CTB201): sc-8419 for P-Selectin/CD62P/SELP antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor^® 488, 594, 647, 680 and 790.
• m-IgG Fc BP-HRP, m-IgG₁ BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for P-Selectin/CD62P/SELP Antibody (P8G6) for IHC(P) applications. These reagents are now offered in bundles with P-Selectin/CD62P/SELP Antibody (P8G6) (see ordering information below).

Информация для заказа

Область использования: Антитела к белкам неспецифической адгезии клеток Антитела к белкам неспецифической адгезии клеток для иммуногистохимии Антитела к белкам неспецифической адгезии клеток для иммунопреципитации Антитела к белкам неспецифической адгезии клеток для иммунофлуоресценции Антитела к белкам неспецифической адгезии клеток для проточной цитометрии Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	100 tests in 2ml
	Кат. номер:	sc-18834 PE
Цена (с НДС 20%):	по запросу	В корзину
Наименование: P-Selectin/CD62P/SELP Antibody (P8G6) PE / P-Selectin (P8G6) PE. Примечание: SQ Category: Primary Antibody Conjugates, Species: , Host Origin: , Applications: IP, IF, IHC(P), FCM, ELISA, UNSPSC: 12352203, datasheet